Hylenex is hyaluronidase. This one is a recombinant or genetically created hyaluronidase. Amphadase and Vitrase are animal-derived products. But all of these are hyaluronidase so they would all have the same pharmacological action. The recombinant drug would be considered less risk especially in those patients that have contrainidcations to animal products. Lynn
Here is a posting on the ASHP website about these shortages dated June 2010:
http://www.ashp.org/Import/PRACTICEANDPOLICY/PracticeResourceCenters/Dru...
To my knowledge, there is no substitute for hyaluronidase when treating an extravasation injury. Eager to know what others are doing as well. Lynn
Lynn Hadaway, M.Ed., RN, NPD-BC, CRNI
Lynn Hadaway Associates, Inc.
PO Box 10
Milner, GA 30257
Website http://www.hadawayassociates.com
Office Phone 770-358-7861
I was wondering if anyone has looked ath te hylenex to see if it would be helpful.
Jose Delp RN BSN VA-BC
Hylenex is hyaluronidase. This one is a recombinant or genetically created hyaluronidase. Amphadase and Vitrase are animal-derived products. But all of these are hyaluronidase so they would all have the same pharmacological action. The recombinant drug would be considered less risk especially in those patients that have contrainidcations to animal products. Lynn
Lynn Hadaway, M.Ed., RN, NPD-BC, CRNI
Lynn Hadaway Associates, Inc.
PO Box 10
Milner, GA 30257
Website http://www.hadawayassociates.com
Office Phone 770-358-7861